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Relationships Between Autoimmunity
Scleroderma, rheumatoid arthritis, type 1 diabetes mellitus, psoriasis, Addison’s disease, pernicious anemia, alopecia areata, systemic lupus erythematosus, and celiac disease are all examples of autoimmune diseases. Vitiligo is also considered to be an auto immune disease. Best vitiligo homeopathic treatment in India is available.
Diagnosis
UV Photograph of Vitiligo White Patch
UV light can be used for diagnosing the disease and measuring the efficacy of treatment in the early stages of this disorder. Skin will change color (fluoresce) under a Wood’s lamp when exposed to certain bacteria, fungi, and changes in skin pigmentation.
Classification Attempts to quantify vitiligo have shown mixed results; although a recent consensus has agreed on a segmental and non-segmental vitiligo scheme (NSV). NSV is the most common kind of vitiligo.
Non-Segmental
In non-segmental vitiligo (NSV), areas of depigmentation are typically symmetric. New patches emerge throughout time and may be generalised across large portions of the body or localised to a single location. Vitiligo universalis is a severe type of vitiligo in which just a little amount of pigmented skin remains. NSV can strike at any age (unlike segmental vitiligo, which is far more prevalent in the teenage years).
The Following Are The Classifications For Non-Segmental Vitiligo:
- Generalized vitiligo is the most common pattern, with vast and widely scattered areas of depigmentation.
- In global vitiligo, depigmentation covers the majority of the body.
- One or a few distributed macules in one area are most common in children.
- Fingers and periorificial areas affected with acrofacial vitiligo
- Mucosal vitiligo is distinguished by depigmentation of the mucosa.
Concomitant disorders with segmental vitiligo (SV) vary in appearance, cause, and prevalence. It is not given the same consideration as NSV. It often affects skin areas related to the dorsal roots of the spinal cord and is unilateral. It has a much more stable/static history and appears to be less associated with autoimmune illnesses than extensive vitiligo. Topical and UV radiation has minimal effect on SV. Segmental Vitiligo can be treated by a carefully selected Homeopathic Remedy prescribed by a Doctor trained in the field.
Differentiation Of Diagnoses
A similar condition caused by persistent chemical exposure is known as chemical leucoderma.
Vitiligo, on the other hand, poses a risk. Triggers include inflammatory skin conditions, burns, intralesional steroid injections, and abrasions.
Other ailments with similar symptoms include:
- Albinism
- Halo nevus
- Idiopathic guttate hypomelanosis (white sunspots)
- Piebaldism
- Alba Pityriasis
- Primary adrenal insufficiency causes hypopigmentation following inflammation.
- Macular hypomelanosis that progresses
- Tinea versicolor
- Leprosy.
Relationships Between Autoimmunity
Vitiligo is linked to Addison’s Disease, Hashimoto’s thyroiditis, scleroderma, rheumatoid arthritis, type 1 diabetes mellitus, psoriasis, pernicious anemia, alopecia areata, systemic lupus erythematosus, and celiac disease.
Two of NALP1’s inflammatory products are caspase one and caspase 7, which activate the inflammatory cytokine interleukin-1. Interleukin-1 and interleukin-18 levels are elevated in vitiligo sufferers. In one of the mutations, the amino acid leucine in the NALP1 protein was replaced by histidine (Leu155 His). Humans, chimps, rhesus monkeys, and bush infants all contain the original protein and sequence, which has been highly preserved throughout evolution. Vitiligo patients may also have Addison’s disease (an autoimmune degeneration of the adrenal glands).